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KMID : 0363420170310030024
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Journal of Korean Oriental Pediatrics
2017 Volume.31 No. 3 p.24 ~ p.36
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Review of Clinical Researches for Herbal Medicine Treatment on Cerebral Palsy
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Lee Bo-Ram
Shin Hye-Jin
Lee Ji-Hong
Chang Gyu-Tae
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Abstract
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Objectives: The purpose of this study is to provide clinical evidence of herbal medicine treatment for cerebral palsy by reviewing randomized controlled trials conducted in China.
Methods: We searched literatures dated up to 17 May, 2017 in China National Knowledge Infrastructure (CNKI), and evaluated methodological quality of those studies using ‘Risk of Bias’ tool.
Results: Sixteen studies were selected for analysis. These studies indicated that the total effective rate, motor function,
self-care, muscle spasticity were significantly improved in the herbal medicine treatment group, as compared to the
control group. The most-commonly-used herbs were Poria (茯?), Astragali Radix (黃?), Glycyrrhizae Radix (甘草),
and Atractylodis Rhizoma Alba (白朮). There were no serious adverse events found that were associated with herbal
medicine treatment. The methodological quality of included studies was generally unclear or low.
Conclusions: This study shows that the herbal medicine treatment can be effective and safe in treating cerebral palsy. Further well-designed clinical trials with high methodological quality and appropriate assessment tools need to be performed to solidify these findings.
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KEYWORD
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Cerebral palsy, Herbal medicine, Review
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